Jul 21, 2021 · Because the cancer cells don't have these proteins, hormone therapy and drugs that target HER2 are not helpful, so chemotherapy (chemo) is the main systemic treatment …

Dec 2, 2025 · Triple-negative breast cancer treatments may include surgery, chemotherapy, and more. Learn about the different ways triple-negative breast cancer can be treated.

Dec 23, 2024 · TNBC does not have as many treatment options as other types of breast cancer. This is due to the lack of hormone receptors on the tumors, which makes treatments such as …

Sep 17, 2025 · Pembrolizumab in combination with chemotherapy is FDA-approved as a first treatment for metastatic triple negative breast cancers that are PD-L1-positive (programmed …

Sep 12, 2023 · There are two types of targeted therapies currently available for TNBC: antibody-drug conjugates and PARP inhibitors. Antibody-drug conjugates (ADCs) attach to …

Jun 3, 2025 · Since 2018, five new therapies have been introduced into clinical practice for the treatment of advanced TNBC and include olaparib, talazoparib, pembrolizumab, sacituzumab …

In this review article, we discuss recent advances in treatment strategies for patients with mTNBC including the use of immune checkpoint inhibitors, targeted therapies, and antibody–drug …

May 31, 2024 · Chemotherapy involves using medicines to kill cancer cells or stop their growth in the body. In the past, it was the only treatment available for patients with metastatic TNBC. …

Feb 28, 2025 · Two therapies, talazoparib (Talzenna®) and olaparib (Lynparza®), were approved for metastatic, HER2-negative breast cancer in 2017-2018 and are effective in patients with …

Jan 3, 2024 · These breast cancers can be treated with drugs that target the HER2 protein in cancer cells to slow those cells' growth and kill them. How is triple-negative breast cancer …