Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what ...

This new review article highlights the pivotal and paradoxical role of R-loops in maintaining genomic stability while simultaneously posing risks to it. These three-stranded nucleic acid structures, ...

A research team at The University of Osaka revealed that the loss of heterochromatin can cause a chain reaction leading to ...

A new study by researchers at the German Center for Infection Research (DZIF) and Heidelberg University Hospital has identified RNA:DNA hybrids, known as R-loops, as structural features that guide the ...

Image Caption: The factors contributing to R-loop formation. Several factors contribute to R-loop formation, including RNA components, specific DNA structures, histone and RNA modifications, ...