Classic nuclear export signals (NESs) confer CRM1-dependent nuclear export. Here we present crystal structures of the RanGTP−CRM1 complex alone and bound to the prototypic PKI or HIV-1 Rev NESs. These ...
The fruit fly lacks the tRNA nuclear export receptor Exportin-t, which only exports end-processed tRNAs to the cytoplasm to ensure the completion of the processing steps in the nucleus. The related ...
During eukaryotic gene expression, different classes of RNA molecules are synthesized in the nucleus and are exported to the cytoplasm by mobile export receptors. Export of tRNA requires a specific ...
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