The orbitofrontal cortex (OFC) is critical to identifying task structure and to generalizing appropriately across task states with similar underlying or hidden causes. This capability is at the heart ...

Imagine a future where the grip of cocaine use disorder can be loosened, where cravings fade, and the risk of relapse diminishes. A new study published in Science Advances, led by Penn Nursing's Heath ...

A new study published in the journal Addiction Neuroscience provides evidence that cannabidiol may help prevent the heightened behavioral response associated with the combined use of cocaine and ...

As a whole, cocaine-associated electrocardiographic abnormalities are well described in the literature (primarily in the form of observational studies, small controlled studies and case reports). Upon ...

Cocaine, a drug of abuse, activates just a portion - 10 to 20 percent - of the neurons in the brain's nucleus accumbens, a critical region linked to motivation and addiction. Though small in numbers, ...

The drug semaglutide—licensed for diabetes under Ozempic and weight loss under Wegovy—could help to reduce cocaine addiction. Scientists from the University of Gothenburg in Sweden and the University ...

A United Nations report found a rise in users, confiscation and deaths as cocaine trafficking expands into Africa and Asia, and violence spreads into Europe. By Genevieve Glatsky Genevieve Glatsky ...