ATP, the fuel of life, is produced in mitochondria of living cells by a molecular machine, the ATP synthase. We have isolated the machines from four fungal species, compared their stabilities and ...
Top left shows how the in vitro aggregation of the protein TDP-43 (associated with ALS), seen as white blobs, is dependent on the concentration of ATP (measured in millimolar, mM). The same is shown ...
ATP has been found to regulate cytosolic viscosity and thereby protein aggregation, which can lead to synaptic dysfunction and neurodegeneration. NMN (nicotinamide mononucleotide) is a precursor to ...
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